![]() Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals. Utilizing the multiparameter capability of the ZE5 to Monitor T Cell Exhaustion and Effects of Immunotherapy (PDF 771 KB) Immune Surveillance in SARS-CoV-2 Vaccine Development (PDF 112 KB) Seamless integration into automated workcells and LIMS.Detection of pro-inflammatory cytokines and cytokine receptors.Evaluation of T cell-stimulating viral epitopes for vaccine candidates.Rapid discovery of neutralizing antibodies.High-parametric antiviral immunophenotyping.Profile virus- and vaccine-induced immune responses with the ZE5 Cell Analyzer. Cell Phenotyping with the ZE5 Cell Analyzer Large-scale assays can benefit from automated high-throughput, high-parameter, multiplex flow cytometry to identify treatments faster. Immunophenotyping is used in vaccine development to characterize the immune response of the host and identify key immune players for attenuating viral infectivity or replication. Perform Immunophenotyping with Flow Cytometry Moreover, cytokine profiles in disease state and treatment groups can elucidate the immune response associated with vaccine dosing. These cell phenotypes and antibody profiles are complex, but measuring these responses allow researchers to glean insights into whether immunity is achieved. Measure Vaccine-Mediated Immunity for Vaccine DevelopmentĪ challenging step in vaccine development is characterizing the host immune response and identifying key mediators of efficacy.
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